Epsom Flush

Epsom Flush.png


Epsom Flushes may be used for relief of constipation, to reduce a body burden of mercury and other toxins, and to rebuild our body cells, organs and systems.  After your initial Epsom Flush, The Wilking Protocol requires that you have bowel movements several times a day.  The Epsom Flushis used for constipation, for detox, and for slowly helping our bodies rebuild with the essentials for our well-being.  The Epsom Flushis NOT being used to treat a symptom, like constipation, instead it helps to solve the problem causing constipation.
Pregnant women should not do a full on Epsom Flush, as contractions have been known to cause
miscarriage or preterm labor.  However, if you avoid contractions, I see no reason a pregnant women cannot use our essentials to achieve loose bowels. 

Incredibly, the Mayo Clinic recommends a product like Colace for constipation during preganncy.  The active ingredients of Colace:

Docusate Sodium 100mg. Inactive Ingredients: D&C Red No. 33, FD&C Red No. 40, FD&C Yellow No. 6, Gelatin, Glycerin, PEG 400, Propylene Glycol, Sorbitol, Titanium Dioxide.

Nursing women may have concerns about releasing retained toxins through their breast milk.  A baby’s body composition is almost identical to the mother’s, and this includes a body burden of mercury and other toxins.  A baby may need a detox as much, or more than mom needs it.  For concerned mothers, I recommend expressing milk before doing the Epsom Flush.

Do not perform an Epsom Salt Flush until you understand Epsom Salt Basics.


Caregivers should not have a child do an Epsom Flush unless they have personally experienced it multiple times, and fully understand its application. 

As always, check with your doctor to see if The Wilking Protocol, and an Epsom salt flush is right for you. 

Magnesium sulfate is often called Epsom salts.  The Wilking Protocol uses Epsom salts for the laxative effect of magnesium, and for the detoxifying effect of sulfur.

Most recommended laxatives run through the intestines as if they were a hollow, lifeless tube.  For example, doctors often recommend polyethylene glycol 3350, Miralax, for a clean out.  PEG has NO nutritional benefits or use in a human body.

For anyone who has used, or currently uses products containing paracetamol, also called acetaminophen, their livers may be chronically deficient in sulfur.  Tylenol and other over the counter medications containing acetaminophen can seriously damage the liver by creating acute, and/or chronic deficiencies in glutathione.  Without glutathione, we cannot detox from toxins like mercury, which is injected, implanted, and prescribed to us in mercurial treatments.  Our liver and body will not detox if we do not produce enough sulfur-based glutathione.  Every year in the USA, for overdoses of acetaminophen-containing products, there are more than 75,000 EMERGENCY ROOM VISITS!


From sulfur, our body makes the connective disulfide bonds necessary for healthy intestines, hair, skin, and joints.  Insulin, the peptide hormone produced by the pancreas, requires disulfide bonds. 

An Epsom salt flush provides a large dose of essential raw materials, causing the body to release retained toxins, and excess nutrients.  This allows the body to retain some magnesium and sulfur, vital essentials for our cells and systems, but also prevents the body from redistributing toxins without sending them out the door.  It is very important that you provide an outlet for toxic redistributions.

As an analogy, think of rush hour traffic without any traffic control, and the resulting frustrated drivers and accidents.  The Epsom Flushsends magnesium and sulfur into the system, but also clears out the roadways, before the entrance of the next series of vehicles.  This prevents our bodies from being overwhelmed by getting too much too fast, where the body cannot handle the detox.  A large increase in essentials, and no reduction in traffic, can create unnecessary oxidative stress.  Flushing with magnesium sulfate quickly cleans out the liver and intestines, thus limiting the redistribution of toxins, and preventing the creation of free radicals, making for a safe end effective method of detoxification.

“Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA.  Oxidative stress from oxidative metabolism causes base damage, as well as strand breaks in DNA.”

By flushing the intestines and the liver, the Epsom Flush takes the stress off the rest of the body, especially our other detox systems; the kidneys, lungs and skin.  The flush creates a vacuum, or a void if you will, where the liver once again opens up for business.  Our cells, organs, and systems then find a release of retained toxins won’t just end up redistributing them in a closed system, and instead are safely sent to the cleaned out liver.

By giving your body a single large dose of Epsom, you are acting as the traffic controller.  You have let the traffic, magnesium and sulfate, enter your body in a large dose, a large pulse of traffic, and enough of it so that the body is ‘flush’ with these essentials, and then can let the excess go with a bunch of retained toxins. 

Think of the accidents and the frustrated drivers if they entered a traffic system that was a closed loop, where the large highways (your intestines or other detox pathways) were closed for business, and the traffic (needed nutrients) were all directed through the nearby towns and villages.  Then, after navigating through those streets, the traffic was detoured back to where it started, and had to do it all over again.  The scene would be a travesty, with vehicles wrecked or abandoned, as they ran out of gas or the drivers simply left them behind in frustration.  This is constipation, and it can cause serious mental health and physical problems. 

The root of depression may be a constipation problem caused by mercury, and/or other drugs, often called ‘inhibitors.’


Over time, as you do Epsom Flushes, you will become expert at managing doses, timing, and your results.

During an Epsom Flush, the intestines may be cleared of contents relatively quickly, but there may also be a delayed action.  

The magnesium and sulfur may be drawn from the intestines up through the portal vein into the liver.  This will delay a flush, and I have seen it take as long as 24 hours for results.  However, that is highly unusual, and results are usually seen within 4 to 8 hours.

“The portal vein, or hepatic portal vein, is a blood vessel that carries blood from the gastrointestinal tract, gallbladder, pancreas and spleen to the liver.”

There may also be a combination of intestinal clearing, and the delayed clearing of the liver and bile ducts.  This likely occurs when a person initially flushes clear, and then later in the day the flush comes again, with dark or multi-colored evacuations, and sometimes solids.  Many have reported seeing gallstones and mucus, or pathogens like candida and liver flukes.
When the Epsom draws up through the portal vein into the liver, the gallbladder and liver will flush bile, naturally colored green, and/or yellow, and may give the evacuations an unusual coloration.  Bile digests the fats in our foods, but also kills undesirable bacteria.  Our bodies make more than a half-liter of bile a day.  Releases from the bile ducts enter the digestive tract at the duodenum, just below the stomach.

Flushing with Epsom releases old bile with retained toxins from the body.  Looping bile with retained toxins may cause very serious problems.  Think once again of that closed traffic system, and the accidents and frustrated drivers.

Who needs an Epsom Flush?
Anyone with a chronic condition may benefit from an Epsom Flush.  Think of chronic conditions as stagnant conditions, with that closed traffic loop, and no resolution to it.  The eczema or psoriasis is constant, the arthritis flares, the candida is never quite resolved, and Lyme disease turns chronic.

Sulfur is the 8th most common element in the human body, so doing an Epsom Flush is not a one-time thing.  Even though we don’t want to overwhelm our systems with a constant influx of additional essentials, we still need them regularly.  Sick people are deficient in necessary essentials.  Once detox pathways open, once the intestines are again open for business, then more essentials may be ingested, and they may be ingested more often as a matter of routine.  Until that time, it is wise to use caution.

When we breathe in life giving oxygen, we also exhale the by-product of it.  This is why intermittent Epsom Flushes work.  We take in the goodness, and then we release the excess and by products of it.  Practice in with the good, and out with the bad.  Repeat, in with the good, and out with the bad.

Do not take Epsom salts and remain constipated.  Avoid closed loop systems.  You need the release.

Do one Epsom Flush, and that will mitigate resulting responses.  Once responses have stabilized, then again do the Epsom Flush.  You act as traffic control for your own body.  Aim for one Epsom Flush a week, until you can hear what your body is asking for, and until you are fully regular.

Until you have experience doing Epsom Flushes, I do not recommend doing them away from home.  For your first time, stay home, and take the day off.  It will be very difficult for you to determine the timeline of your initial flushes.  As per the reasons given above, you will not know to where the magnesium and sulfur are being directed, nor will you know what they are moving out of your organs. 

Make sure you have a bathroom available.  I have not heard of anyone being incapacitated by a flush, so if you have kids you should be fine, just be clear with them that you may be making ‘runs’ to the toilet. 

A larger single dose may be less likely to make it to the liver, and the excess Epsom will release from the intestines.  Commonly, initial flushes are relatively quick and easy, and then after 4 or 5 of them, delayed flushing may start, as the body begins absorbing the magnesium and sulfur, with the intent of detoxing the liver.

Pre-Epsom Flush
Every human being needs vitamin C in good quantity, every day, preferably twice a day.  It serves everyone to have a body flush with vitamin C.  Make sure you get at least two good servings of vitamin C daily.

For anyone regularly drinking coffee or alcohol, you may be chronically deficient in Thiamine.  Getting Thiamine levels restored may be tricky as retained toxins are released.  Taking a high dose of thiamine before a flush will allow levels to be restored, without creating that previously described closed toxic loop.  http://www.mercuryfreekids.org/mercury101/2018/1/21/thiamine-saves

The night before the flush you may want to take as many as two teaspoons of Epsom in water right before sleep.  This can prepare you to flush first thing in the morning.  There is a possibility you will awake in the middle of the night with the runs.  If this happens, you may treat this as your successful first flush.  There is no reason to take more Epsom to force something. 

Before your flush, and you may do this the night before, you may add in 10 to 50mg of Manganese.  This will help your body make Ariginase, that also makes L-Ornithine.   L-Ornithine plays a part in the Urea Cycle.  It turns ammonia into Urea that will be sent to the kidneys, and that will help take any stress off your liver.


How to Epsom Flush
Use a USP grade Epsom Salts, with directions on the side of the packaging for how to use it as a laxative.  Epsom Salts can commonly be found in grocery stores and pharmacies. 

There is no exact science to an Epsom Flush.  The basic rule is, take more than you need.  This may appear counterintuitive, but by taking a large dose, the Flush is much more likely to be completed in full, with a good evacuation of toxins and the excess Epsom.

Dosages – Common methods

If necessary, you may add anything you like to mask the taste of the Epsom salts.  Juices of lemon, orange, apple or any other juice is fine.

Taking citric acid in the form of lemon water can be beneficial, and help the flush go more smoothly as the lemon will cause the organs to ‘pucker,’ to tighten up and dump their retained contents/toxins.  Think of how sucking on a lemon causes your mouth to pucker.

Apple juice is great to take with a flush as well.  Apple juice, or Apple Cider Vinegar has malic acid, and malic acid will also cause the organs to pucker.  Malate is part of the citric acid cycle which is a series of chemical reactions which our body uses to release stored energy.  This cycle literally happens billions of times every millisecond in our bodies.


It can take between 1-8 teaspoons of Epsom salt to loosen the bowels enough to flush, depending on the amount of retained toxins, and if there exists a deficiency of essential magnesium and sulfur.  Bodies deficient in them may be inclined to retain the elements

My recommendation is to take 1 teaspoon of Epsom in 12 to16 ounces (300 to 450ml) of water every 15 minutes, up to 8 doses.  You may find that you need less water when approaching the later doses.  In about 2% of the Flushes I have encouraged, and that is in the range of 300-500 people, there have been about 10 people total that have vomited.  It is not completely clear why this happens, except that the person’s body may want to completely remove toxins, and they may be up in the stomach.  Epsom is not pleasant tasting, so it may simply be the ‘disgusting’ factor has added to this as well.

Many people have had better experiences with larger doses initially.  If you choose to do so, you may take 2 teaspoons of Epsom per glass, for up to a maximum of 4 doses.

Here are some other methods for an Epsom Flush:

'To treat constipation with Epsom salt, follow dosage guidelines. For adults and children 12 years old and older, dissolve 2-4 level teaspoons of Epsom salt in 8 ounces of water and drink immediately.  For children 6 to 11 years old, dissolve 1-2 level teaspoons of Epsom salt in 8 ounces of water and drink immediately.'

Epsom salt usually produces a bowel movement within 30 minutes to six hours.  A dose or two should clear up acute constipation.”

Although many websites have warnings not to give small children Epsom salts, I can find no verified reason as to what is the actual danger.  Instead, Western Healthcare prescribes proven poisons like Miralax.

According to this website:
'For children of above 1 year age, take 1/2 teaspoon in cup of cold water or juice.'

My recommendation is to proceed with caution, and as a caregiver, you should always administer a treatment to yourself first, before doing it with a child.

After the Flush
For those just starting Epsom Flushes, many times the skin on the buttocks and around the anus may grow irritated from the release of retained toxins, and high PH, caustic bile.  Washing will help reduce the burn, as well as applications of coconut oil, olive oil, and/or castor oil.  Many benefit from a product called Willard’s Water.  Use as directed.

Not everyone feels great after a flush, but in my experience I have found people feel better and better after every flush.  Some people feel drained after flushes, and this is quite normal.  Its possible their liver had accumulated quite a bit of toxins, and letting go is traumatic.

For the first Epsom Flush, some people get a good clean out of the liver right away.  As described above, these people may just be cleaning out their intestines with the initial flushes.  For others this may come later, where the body needs more of the Epsom to flush, and there is a delayed flush.

Be wary of taking small amounts of Epsom as a daily dose until you have a full understanding of how it works within your body.

Some people stir up so many toxins during a flush that it is wise for them to take charcoal, to get their bowels to settle down.  One or two grams of charcoal may help.  Keep in mind that for some people charcoal can be constipating, and your body may also be inclined to constipate itself after a flush, basically closing the door so it doesn’t lose any more of the desired magnesium and sulfur.

Vitamin C will move mercury out of the blood stream and into the liver.  Getting a good dose of Vitamin C after an Epsom Flush is recommended. http://www.mercuryfreekids.org/mercury101/2017/12/5/mercury-roundup

Ingesting fats will also help the body stop newly released mercury from redistributing, and it may also cause the organs to continue flushing the bile.
After you have taken your doses of Epsom, and had an initial flush, you may eat, and foods high in fat are recommended.  If after 4-6 hours and you still have not Flushed, then it is wise to eat.  Stay close to the toilet.

Homemade sauerkraut is greatly beneficial to our health.  Sauerkraut was used to prevent scurvy in the golden age of sail.  The curing of the cabbage produces vitamin C!   This is the BEST way to get probiotics, salt and vitamin C together in an all natural from.

You may feed your intestinal microbiome with probiotics after you cleanse.  The best probiotic is your own homemade sauerkraut.  It's incredibly easy to make.  If you do not have your own sauerkraut available, I recommend Bubbies Sauerkraut.  Bubbies is not pasteurized (heated) so it is loaded with probiotics, and is much much better than any expensive probiotic on the market.

Milk products like whey, or yogurt and kefir may be beneficial.

Epsom salts for some people may make their joints and muscles ache.  Lecithin, and the reduced forms of it, Choline/Inositol can help reduce excess sulfur in the body.

Citric Acid
Store bought citric acid, commonly found in the baking aisle of the grocery store, is commonly made with aspergillus fungus.  For a person with a mold sensitivity, they may want to use lemon or lime rather than a food grade citric acid.   I recommend you use lemon. 

Some people may have a reaction to citric acid.  Our bodies use a process called citric acid cycle.  If we have a compromised citric acid cycle, we can get stuck, where our body can end up using some other much less efficient system for our energy, a system like Glycolysis, where we have a constant malaise, never having enough energy.



If you choose to add a powdered citric acid, try and make sure it is NOT from a company that has anything to do with Coca-Cola.  In the Good Ole USA 20% of our Citric Acid is made by Coca-Cola owned subsidiaries using a mercuric-chloride process.  Their form of Citric Acid may have mercury in it! http://www.mercuryfreekids.org/mercury101/2016/8/3/the-mercury-in-corn-syrup

The idea of letting go can be quite scary for people.  Historically, diarrhea in the form of cholera or dysentery could mean death.  I believe that fear of diarrhea may be an archetype, like an innate fear of snakes. 

This is not an intuitive process.  We have been taught to hold onto our ‘stuff.’  How many times have you heard the saying, “Keep your shit together.”

I have never ever heard of anyone having any sort of a problem with gallstones using my protocol.  Many people have reported seeing all kinds of contents including liver flukes, parasites, candida globules, black and white seed like things, squid looking oddities, and floating gallstones.

In the words of the famous ogre SHREK, “Better out than in I always say.”

More on Bile Ducts
“Blockage of the bile duct by gallstones… (or any number of  other reasons) …prevents the bile from being transported to the intestines.  Instead, the active ingredient in the bile (bilirubin), accumulates in the blood. This condition can result in jaundice, where the skin and eyes become yellow.  It can also cause severe itchiness from the bilirubin deposited in the tissues.  In certain types of jaundice, the urine will be noticeably darker, and the stools will be much paler than usual.  This may be caused by the bilirubin going into the bloodstream and being filtered by the kidneys into the urine, instead of some being lost in the stools…”

Epsom Flush Summary
Don’t get caught up in the details.  All you need to do the flush is a couple of glasses of water, and a few ounces of Epsom Salts, and off you go.  You will do fine.  Don’t worry.

Good luck with your flush, let us know how you do.

Albert Wilking

I want to thank all the members of the Wilking Protocol Group for their contributions and research.  Special thanks go out to the moderators and administrators of the group, that have helped make the group a safe place to research and recover.  

Vanessa Wilking
Dejean O’Bryan
Maree Kratzer
Ann Gunn
Mark Paulson
Jeanette Hansen
Judith Ann Von Wald
Martinez Leanne
Ginger Pett Rosenberg
Scott Taylor

Thank you!

Special mention to Maree Kratzer, who kept after me about getting this post done!

Flush To Start.jpg

If you have found this page helpful,
please leave your comments,
and reviews in the Discuss Comments section
at the bottom of this page.


I recommend products that are natural to our well-being, and only ones that can be found in the grocery or health food store.  Everything I recommend I do myself.  Everything I do is on my website, and everyone can use my site to get back to feeling great, naturally.  However, some people can be very deep in the woods, allergic to just about everything, while suffering from chronic pain and inflammation.  Helping people naturally, takes time, patience, attention to detail, and experience.

Albert Wilking

This is the Facebook Page for The Wilking Protocol. 
Please join our knowledgeable and supportive team.


These links contain the basics of The Wilking Protocol.  Please read them in the order given.

The Wilking Protocol
Are You Mercury Toxic? 
Epsom Salts - Holy Grail of Healing
Salt Is Life
Potassium - Let The Truth Be Told
Vitamin C or Your Life

Magnesium, Inflammation and Nerves
The Power of Iodine

Celery, Nitrate and the Microbiome
Thiamine Saves

For Albert Wilking’s personal support click
Get Help Now!

Mutants R Us

TWP-Mutants R Us.png


In regards to genetic mutations, the MTHFR gene, or others; we are all mutants.  Everyone has MUTANT genes, but every one of us needs the same basic essentials for human life.  We need Oxygen, Sulfur, Vitamin C, etc, and we all need them in about the same amounts.. 

We don’t solely breathe in oxygen, taking in the good stuff all the time.  We also have to exhale, to carry away our metabolic waste products.  When we take in essentials, we have to have our internal sanitation departments ready to deal with the garbage created by our use of the good stuff.  Our bodies have to be able to take out the trash.  Our bodies work hard to limit oxidative damage under normal stresses.  If we have contact with toxins, if we have retained toxins or we are redistributing toxins, then we will need more essentials for our bodies to detox and rebuild.  Coming in contact with toxins can make us go deficient in essentials, and this can cause us to shut down our internal sanitation departments.  However, taking in essentials without opening the detox pathways is a very bad idea.  Knowing how to do find this balance, comes from experience, and intuition.

Giving our bodies essentials to function, we step into Macro-Management, not Micromanagement.  When we give our bodies the good stuff, our brains, our thoughts, can then concentrate on greater interests.  We act more Responsible, more like the ‘HEAD’ of our own corporation, with that corporation being our own body.  We act less like disgruntled workers yet again called into Human Resources for some outlandish behavior, or for the umpteenth time sent to the First Aid department.  Here are a couple of examples of Micromanagement.  “I put myself on this weird diet because ‘Mr Expert’ told me it was a good thing, and I believed him, and I promised myself I would do it, and I don’t want to go back on my word.” “I keep taking these supplements, these drugs, these treatments.  I’m not getting better, and in fact, I’m feeling worse and worse.”  These are examples of someone forcing something on their body, like a CEO of a company telling the workers how to do their jobs.  Stop telling your workers, your body, how to do their jobs.  Give your body what it needs to function, and then get out of the way.  Stop Micromanaging your body.  

Let’s go back to the genes.

Our genes express themselves differently depending on the circumstances, and this applies to everyone and everyone’s genes.  Just because a person has a marker on their genes for some genetic ‘problem’ doesn’t mean anything.  However, it will mean something if that genetic marker keeps being expressed over, and over, and over again.  For a ‘Micromanager,’ someone that keeps forcing something on their body, their genetic expression, translation, transcription, whatever we want to call it, that can cause some part of the gene to be expressed.  Think of the smoker, or the person overeating, or drinking, forcing it on themselves over and over again.

I see everyone the same, no matter what their genes.  Its the genetic expression that counts, and not whether we have a ‘marker’ for a possible genetic outcome.  People in the business of selling genetic testing, are in the business of selling Micromanagement.  They want you to think what they are doing is important to you and your well-being. 

Mercury poisons on the way in, and it poisons on the way out.  Genes express themselves based upon that with which they come in contact.  Keep redistributing mercury without providing a solution to a constant, unwavering redistribution crisis, and your body will step in and take care of the problem.  Your body will express its genes differently depending on that to which it is exposed.
One more time:

Genes express themselves depending on what, and with whom they are in relations.  If you as the CEO, the President of your body, if you keep forcing something onto your body, your body and your genes are going to react to it.  I understand your body may have genes that are more likely to make cancer, gain weight, or have some kind of neurological condition as compared to the next person.  What I want you to do is to remove, or limit those influences on your genetic expressions.  If the neurotoxins, the bad influences are gone, those ‘bad’ genetic markers will not be expressed.

We do NOT have a specific gene that makes us have an anus, an ear, or a belly button.  For example, there is NO such thing as a heart gene.  What happens is when the body makes a cell, it makes it based upon the genes, but that gene expression is in relation to the other neighboring cells.  Your cells follow the herd, and the herd is the neighboring cells.  That newly made cell does what the rest of the gang is doing.  If you keep expressing genes that deal with mercury in a 911 redistribution mode, you are going to end up with some kind of genetic problem.

Heart cells aren’t made for carrying a bunch of toxins.  They are the crew that is going to the gym, everyday, all day, 7 days a week.  The body feeds the heart cells what they need to be heart cells, it grooms them to be workout “Kings and Queens.”  Heart cells aren’t designed to store anything, they are marathon runners, and therefore a neurotoxin like mercury can be disastrous to them.

We all have predisposed genes for handling toxins, and if a toxin like mercury keeps showing up, eventually the body goes, “We gotta stop these mercury atoms from wrecking the place.  We need to do something about this.”  This is where the gene expression comes in, and it plays into it all along.  “If we don’t do something about the mercury continually entering the cardiovascular system, the heart gang may have a heart attack, and then we’re all dead.”

Genetic expressions show up in how the body handles this extreme problem.
The body may flip a switch and start using fat cells as mercury storage sites.  When we move mercury, we start putting on weight, and if you don’t know what’s happening, it can seemingly happen for no reason at all.

For someone else, the way their body may deal with a neurotoxin like mercury, rather than make a gaggle of cancer or fat cells, they may stuff it into nerve cells.  The mercury may go into the joints and then we have ‘Rheumatoid Arthritis.’  Rheumatoid Arthritis is a name someone made up for a general condition.  It is currently classified as an autoimmune disorder, and we are told the causes are unknown.  However, I’m sure soon enough the Micromanagers will find the genes for Rheumatoid Arthritis.

Yes, you may have more difficulty than someone else with some of the basic supplements to human life.  Yes, your genes may be expressing a certain way in the presence of toxins like mercury.  This may be giving you acne, ALS, arthritis, brain fog, cancer, multiple sclerosis, psoriasis, and the list goes on and on.

Most of us that have been educating ourselves, working to feel better, have at least one shelf of supplements collecting dust.  Put what you think you know about your genes on that shelf for right now.  You can always go back to it if you need to.  Let’s let our genes do their jobs, and that means we do our job of giving our body what it needs to do its job, and then we get out of the way.  We stop micromanaging our body.

Here are a couple of quotes from Wikipedia’s Gene Expression article.

“Regulation of gene expression refers to the control of the amount and timing of appearance of the functional product of a gene.  Control of expression is vital to allow a cell to produce the gene products it needs when it needs them; in turn, this gives cells the flexibility to adapt to a variable environment, external signals, damage to the cell, and other stimuli. More generally, gene regulation gives the cell control over all structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism.

The following quote comes under the sub-category of ‘Transcriptional Regulation’ from the same article

More recently, it has become apparent that there is a significant influence of non-DNA-sequence specific effects on transcription.  These effects are referred to as epigenetic and involve the higher order structure of DNA, non-sequence specific DNA binding proteins and chemical modification of DNA.  In general, epigenetic effects alter the accessibility of DNA to proteins and so modulate transcription.”

If you have found this page helpful,
please leave your comments,
and reviews in the Discuss Comments section
at the bottom of this page.


I recommend products that are natural to our well-being, and only ones that can be found in the grocery or health food store.  Everything I recommend I do myself.  Everything I do is on my website, and everyone can use my site to get back to feeling great, naturally.  However, some people can be very deep in the woods, allergic to just about everything, while suffering from chronic pain and inflammation.  Helping people naturally, takes time, patience, attention to detail, and experience.

Albert Wilking

This is the Facebook Page for The Wilking Protocol. 
Please join our knowledgeable and supportive team.


These links contain the basics of The Wilking Protocol.  Please read them in the order given.

The Wilking Protocol
Are You Mercury Toxic? 
Epsom Salts - Holy Grail of Healing
Salt Is Life
Potassium - Let The Truth Be Told
Vitamin C or Your Life

Magnesium, Inflammation and Nerves
The Power of Iodine

Celery, Nitrate and the Microbiome
Thiamine Saves

For Albert Wilking’s personal support click
Get Help Now!

Genetic Wizards



Beware of those claiming to have 'knowledge' about your 'special' genetic mutations.  Everyone has 'special' gene mutations.  Ask yourself, "Is genetic testing feeding my EGO?"  Ask yourself if you are proud that you have 'special' genes.  At first this may not seem to make sense.  After all, who would want to be 'sick?'  Who would want to have gene mutations?  For me personally, one of the most caring remembrances I have of my family growing up was when I was sick.  When I was sick, I got attention.  If I have a label of 'Gene Mutant', does this make me special?  Do I get attention because I have special needs?  I'm not saying that gene mutations do not exist, I'm saying there are way more important parts of the human story than my 'special' genes.

This link gives a tragic story of genetic testing is being used deny payments to families whose young children have been destroyed by the healthcare industry.  It is sad, very sad, but please read: 

A good guide for our well being is KISS, "Keep It Simple Stupid." 

If we don't get Oxygen, we die within 10 minutes.  If we don't get Vitamin C, or salt for about 2-3 months we are dead.  Let’s concentrate on the essentials to human life.  Every human needs some basic essentials not only to survive, but to properly function.  If we don't get them in excess, our bodies will limp along, struggling to survive. KISS.

For those with the MTHFR gene, beware of a supposed problem of assimilating folate, or folic acid.  For our survival, for us to function, our microbiomes make folate.  Beware of Genetic Wizards, and the twisted tales they weave.

This article talks about homocysteine, spina bifida and MTHFR.

“...some people have a genetic variant of MTHFR that changes its activity, leaving fewer folates and more homocysteine accumulating in the body.  Folks with this specific variant likely need to consume more folates.”

“The microbiota of the human colon can produce folates, which can then be absorbed into the body through the colon wall.”

“Abnormally high levels of homocysteine in the serum, above 15 µmol/L, are a medical condition called hyperhomocysteinemia.  This has been claimed to be a significant risk factor for the development of a wide range of diseases, including thrombosis, neuropsychiatric illness, and fractures. It is also found to be associated with microalbuminuria which is a strong indicator of the risk of future cardiovascular disease and renal dysfunction.

Additionally, elevated homocysteine is found in megaloblastic anemia.”

Folate is Latin for foliage.  Our body’s 'chosen' bacteria makes food for the rest of our body.  Chosen means that our body chooses the bacteria it needs, not us trying to 'fix' something.

“…folic acid supplementation and foods fortified with folic acid may be largely ineffective in these people.

This could be a big issue if they have a folate deficiency, high homocysteine or are in the early stages of pregnancy and rely on folic acid.

Some suggest that unmetabolized folic acid can bind to folate receptors, effectively blocking access by L-methylfolate. I couldn’t find any studies to confirm this theory though.

Others also say that unmetabolized folic acid in the blood is uniquely harmful, but there’s no evidence of that in the medical literature.  The body is simply getting rid of excess (a good thing), which goes from blood to kidneys, and then out through urine.”

We can see from these articles, we need more greens, not less.  We need more folate, not less.  Eat more greens.

Our body will choose what bacteria it wants to do the job, that is, unless, we keep interfering the process.  For this reason, I generally do not like essential oils, as I see people trying to 'fix things' that just don't need fixing. This includes taking probiotics to get our gut microbiome 'right.'

If we are getting enough salt, we will make the exact amount of HCL we need to digest our food, and this means that probiotics are for the most part worthless. They get chewed up by the HCL.  They never make it to the intestines. So in essence, probiotics are for salt deficient people, and salt deficient people are invariably sick. They are either not able to properly digest their foods, or their white blood cells that make HOCL, hypochloric acid, to fight infections, won't have enough CL to make the right amount of HOCL to fight infections. Our body gets the CL in the HOCL primarily from SALT, NaCL.

Essential oils will kill off pathogens and bacteria, and this includes good bacteria.  This can be deadly for a mercury toxic person.

It is a scorched earth policy to use pathogen killers, or immune boosters.  We are 'sold' that our bodies are bad, or dumb, and that they need to be fixed.  Instead of believing this, and acting on it, we need to give our body what it needs to function, in great supply, and then the body steps up to the plate and hits home runs.  We need to stop micromanaging our bodies.

“Still other antibiotics fight infections by stopping bacteria from producing folic acid — an essential vitamin — or disputing the structure of a bacterium's cell membrane, which controls how substances move in and out of the cell.”

Be wary of any practitioner that is not telling you that you need SALT or Sulfur.  All they have to do is look at the skin, or ask a few questions to know the answer.  Do you have mercury?   

You don't need Crystal Ball Genetic Tests.  They are designed to keep you as a paying customer, to keep you in the dark and limit the knowledge imparted to you, so you believe you need them for their 'enlightened' services.

Eat more greens, not less.

Albert Wilking

Also see

Sulfur and your Skin

Autism, Ears, Smells, Sulfur, Testosterone, and Vaccines

Acute vs Chronic Mercury Poisoning

Mercury Ping Pong


If you have found this page helpful,
please leave your comments,
and reviews in the Discuss Comments section
at the bottom of this page.


I recommend products that are natural to our well-being, and only ones that can be found in the grocery or health food store.  Everything I recommend I do myself.  Everything I do is on my website, and everyone can use my site to get back to feeling great, naturally.  However, some people can be very deep in the woods, allergic to just about everything, while suffering from chronic pain and inflammation.  Helping people naturally, takes time, patience, attention to detail, and experience.

Albert Wilking

This is the Facebook Page for The Wilking Protocol. 
Please join our knowledgeable and supportive team.


These links contain the basics of The Wilking Protocol.  Please read them in the order given.

The Wilking Protocol
Are You Mercury Toxic? 
Epsom Salts - Holy Grail of Healing
Salt Is Life
Potassium - Let The Truth Be Told
Vitamin C or Your Life

Magnesium, Inflammation and Nerves
The Power of Iodine

Celery, Nitrate and the Microbiome
Thiamine Saves

For Albert Wilking’s personal support click
Get Help Now!

The Flu Scam

Screen Shot 2018-01-27 at 8.59.11 AM.png


To stay healthy, don’t put toxins into your body or anyone else.  Take large enough doses of needed nutrients so that your body flushes toxins, and the excess nutrients.  Stop micromanaging yourself and put your body in charge.  You don't need to do anything else except wash your hands.

Sick people are toxic people.  Toxins cause us to loose needed nutrients, lowering our natural immunity. 


I propose to you that the Parke Davis Phylacogen business laid the ground work for the Spanish Flu of 1918-1920, killing more than 50 million people.

Phylacogen Scam 170608.png

This is the Journal of the American Medical Association from 1913.


This is a discussion about Parke Davis’s Phalacogen scam.  People who cared could see the scam coming.

An excerpt of an article critical of Parke Davis (Pfizer) and their Phylacogen scam.

Our profession – and through it the public – is being exploited by some pharmaceutical houses.  In the editorial department, this week, something is said about “this Phylacogen business: - and, by the way, “business” is a most appropriate word to use in this connection.  Parke, Davis & Co. have taken a dangerous and unproved agent-one that has not passed the test of scientific investigation-and are putting it on the market apparently with but one object in view, that of forcing it on the profession.  Every medical journal of importance that accepts this kind of advertising is getting some of “this Phylacogen business;” every pharmaceutical journal is also getting some of “this Phylacogen business;” every uncritical physician who is willing to gamble with his patients health is getting some of “this Phylacogen business.”  And the public?  Well the public doesn’t matter…

Phylacogen Scam Pfizer.png

These are the results of the Phylacogen Business:

"The publicity being given Phylacogen at present, and certain claims which have been made that the administration of Phylacogen is without danger, seem to demand the publication of the following case:"

From the American Medical Associaton Journal of 1915:
“…We are of the opininon that the therapeutic use of phlacogens is based upon erroneous conceptions of infection and immunity, is unscientific, empirical, and unjustified.  Moreover, there is evidence that their administration is not unattended with risk to the patient.”  Page 1132

The Spanish Influenze Epidemic
Oxford et al (2002, 2005) have suggested that the beginnings of the pandemic occurred in the British military base at Étaples, situated in the north of France (Department of Pas-de-Calais). This military base, which was quite important throughout the First World War, was occupied by 100,000 soldiers within a space of 12 km2. The base was situated near sea marshes with abundant migratory birds. Nearby, there were many farms with pigs, ducks and geese reserved as food for the soldiers, and horses which were used as a means of transport.

Also see

For more on the history of the American Medical Association and the Pharmakons:


Tragically blaming genetics on people for injuries caused by vaccines:


Incredibly, The American Cancer Society never talks about toxic mercury and cancer.


If you have found this page helpful,
please leave your comments,
and reviews in the Discuss Comments section
at the bottom of this page.


I recommend products that are natural to our well-being, and only ones that can be found in the grocery or health food store.  Everything I recommend I do myself.  Everything I do is on my website, and everyone can use my site to get back to feeling great, naturally.  However, some people can be very deep in the woods, allergic to just about everything, while suffering from chronic pain and inflammation.  Helping people naturally, takes time, patience, attention to detail, and experience.

Albert Wilking

This is the Facebook Page for The Wilking Protocol. 
Please join our knowledgeable and supportive team.


These links contain the basics of The Wilking Protocol.  Please read them in the order given.

The Wilking Protocol
Are You Mercury Toxic? 
Epsom Salts - Holy Grail of Healing
Salt Is Life
Potassium - Let The Truth Be Told
Vitamin C or Your Life

Magnesium, Inflammation and Nerves
The Power of Iodine

Celery, Nitrate and the Microbiome
Thiamine Saves

For Albert Wilking’s personal support click
Get Help Now!


Thiamine Saves

Thiamine Saves Banana Bag.png


A banana bag (or rally pack) is a bag of IV fluids that typically contains thiamine, folic acid, and magnesium sulfate, and is usually used to correct nutritional deficiencies or chemical imbalances in the human body.  The solution has a yellow color, hence the term "banana bag.”

This bag of Thiamine and Folic Acid and Magnesium and Sulfate, this formula, this recipe, derogatorily named a “banana bag,” is used to save peoples lives in emergencies.  Every Hospital emergency room has banana bags.

When the doctor calls for a banana bag, the cells in the patient’s body are shutting down; they are dying.  The person will die if they don’t get a banana bag.  End of discussion.  Think about this for 30 seconds.  Visualize it.  Please read this part of the article once more.


Prozac treats symptoms, not life or death emergencies.  Chances are you have heard of the ‘for sale’ product called Prozac.  Before today, had you ever heard of a banana bag saving people’s lives?

Why or why not?

The healthcare industry regulates drugs.  The Federal Drug Administration regulates drugs.  Pharmaceutical companies don’t make money selling ‘Banana Bags.’  They make money by selling their patented drugs to treat the symptoms of deficiencies.  They treat deficiencies of the nutrients in the banana bag.  If you are deficient in Thiamine, Sulfur, or Magnesium, you have ailments.  Chances are you are currently taking drugs that treat the symptoms of those deficiencies. 

The healthcare industry doesn’t want you to take a ‘banana bag’ seriously, or it would be called something like, ‘A Save Your Life Bag of Essentials’ or a ‘Life Giving Blessing.’

Here I have taken excerpts from a wonderful article by David Mayo that explains the importance of Thiamine.


David starts off with a list of symptoms of Thiamine Deficiency:

“Have you been diagnosed with adrenal fatigue?  Have you recently removed processed foods from your diet and had a tough go of it?  Have you been diagnosed with a magnesium deficiency?  Do you:”

Drink coffee or tea
Drink alcohol
Binge on sugar or carbohydrates
Exercise excessively (Crossfit or endurance)
Have poor sleep
Have an altered cortisol rhythm
Have candida overgrowth

“If you said yes to a number of these things, you may be at risk for a thiamin deficiency.  What's worse, if you have cut out processed foods or grains you are probably not ingesting enough thiamin through diet and making your problem worse.  Let's take a look at this rarely discussed nutrient and how it may be contributing to your adrenal fatigue.”

The reason so many of our starches are fortified with Thiamine is that it is so very difficult to get Thiamine from our diet.  If you have cut out wheat and gluten fortified with Thiamine, you lost a very important source of Thiamine for you and your family’s health.

Dave continues…

“…Many people who have undertaken a low carbohydrate diet have noticed a change for the worse in sleeping habits.  Since lowering carbohydrate intake always includes lowering grain consumption and thus thiamin consumption, this is a potential mechanism by which low carbohydrate diets may negatively impact sleep.  The problem may not be in the low carbohydrate status so much as low GABA caused by a lack of thiamin intake.  In people who periodically binge on sugar, overexercise, or drink coffee or alcohol the problem will be worse.  Carbohydrate intake could come in to play once adrenal insufficiency sets in because in the absence of carbohydrate, cortisol is used to increase glucose output by the liver.  Also, since low thiamin has been shown to reduce liver glycogen storage, this would impact your ability to meet the brain's glucose needs when asleep.”

Pow!  Now I am awake at 3am in the morning!  I think this wake up call may actually be a ‘Fight or Flight’ response.  Did I run out of energy to make it through the night?  Our cellular sources of energy are made most efficiently with the Citric Acid Cycle.  Thiamine is required to run the cycle.  If we don’t have Thiamine, we won’t have energy.  I believe that our waking up in the middle of the night isn’t just low blood sugar, but a wakeup call that something is wrong, the body is running out of energy, energy that helps us with our oxygen to survive.  It may even be doing this so we physically move to bring more oxygen into our bodies.

Dave continues…

 “…lifestyle factors that are prevalent in modern society also negatively impact thiamin status.  Coffee and tea contain tannins that render thiamin useless in the body in addition to the diuretic effect that caffeine has that increases the loss of B vitamins.  Alcohol also has a negative effect on thiamin levels both by preventing absorption as well as its diuretic effect.  Wernicke-Kosakoff Syndrome(WKS), a disease of thiamin deficiency, is most often seen in alcoholics.  In addition to its alcohol content, wine contains sulfites that destroy thiamin.

Diseases of thiamin deficiency including WKS and beriberi often present with neurological symptoms, but can include the circulatory system as in the case of wet beriberi.  Candida overgrowth can also lead to thiamin deficiency as yeast use thiamin in the first step of alcohol fermentation.  In addition, 3 strains of bacteria known to reside in the human small intestine and colon are known to produce enzymes that degrade thiamin in the digestive tract, which could become problematic if they overgrow.

Diabetes and high blood sugar can also induce thiamine deficiency and diabetics have been found to be deficient in thiamin.  This is due, in part, to hyperglycemia causing increased loss of thiamin in the urine.  Since it is believed that this effect is due specifically to high blood glucose, whether insulin resistance is pathological due to diabetes or physiological due to low carbohydrate intake would be irrelevant.  In addition, low thiamin has been shown to impair pancreatic function leading to hyperglycemia and thiamin therapy has been shown to improve hyperglycemia in diabetics.”

Dave really nails the Thiamine needs of our bodies!  If you didn’t read the full article, please do so now.  Its important to your well being.   

Please read about Wernicke Korsakoff Syndrome and Beriberi.  Understand that we are being given extreme examples of Thiamine Deficiency.  This may cause us to look at these conditions and then close the chapter.  "OMG!  Thank god I don’t have that condition!  It must be something else."  And off we go searching for another solution.

What we are not being shown is that there are all shades of grey in Thiamine Deficiency.  WK Syndrome and Beriberi have put a person near death.  We may not be near death because of TD, but we still may not be functioning to our fullest potential.

Please review:

Please also review BeriBeri – Thiamine Deficiency


I like how Derrick Lonsdale MD, FACN, CNS, the writer of the following article compares the action of a spark plug to that of Thiamine throughout our bodies.

“Each of our one hundred trillion body/brain cells is kept alive and functioning because of this reaction.  It all takes place in micro “fireplaces” known as mitochondria.  Oxygen combines with fuel (food) to cause burning or the combustion – think fuel combustion engine.  We need fuel, or gasoline, to burn and spark plugs to ignite in order for the engines to run.”

“In our body/brain cells it is called oxidation.  The catalysts are the naturally occurring chemicals we call vitamins (vital to life).  Like a spark plug, they “ignite” the food (fuel).  Absence of ANY of the three components spells death.”

“Antioxidants like vitamin C protect us from the predictable “sparks” (as a normal effect of combustion) known as “oxidative stress”.  Vitamin B1, is the spark plug, the catalyst for these reactions. As vitamin B1, thiamine, or any other vitamin deficiency continues, more and more damage occurs in the limbic system because that is where oxygen consumption has the heaviest demand in the entire body. This part of the brain is extremely sensitive to thiamine deficiency.”



When we don’t have enough Thiamine, our cells begin to starve of oxygen, and the most dangerous and sensitive place where this happens is the Diencephalon part of our brain. 

“The diencephalon of the brain consists of structures that are lateral to the third ventricle, and includes the thalamus, the hypothalamus, the epithalamus and the subthalamus.”

The Diencephalon is the general area of our pituitary, pineal gland, the olfactory bulb that controls our sense of smell, our optic chiasm (vision), and a little control switch called the ‘Habeunlar Nuclei.’

“…Many scientists have begun to examine the Habenular Nuclei's role in motivation and behavior as it relates to an understanding of the physiology of addiction.”

I believe that our addictive behaviors may be triggered by a poor oxygen state caused by a deficiency of Thiamine.  It may literally trigger us to do something, anything, to get the oxygen moving again.

 “Vitamin B1 (Thiamine) is a vital human nutrient that belongs to the vitamin B complex.  It plays an important role in maintaining a healthy nervous system and improving the cardiovascular functioning of the body.

Vitamin B1 is one of the eight water-soluble vitamins in the B complex family. It helps in the conversion of carbohydrates into glucose, which in turn is used to produce energy for carrying out various bodily functions.  Vitamin B1 is also required for the breakdown of fats and protein.

In addition to these health benefits, it maintains the muscle tone along the walls of the digestive tract and promotes the health of the nervous system, skin, hair, eyes, mouth, and liver.  It also improves the body’s ability to withstand stress and is often called the “anti-stress” vitamin.”


Let’s do a recap.  The Healthcare industry calls life giving essentials in emergencies banana bags.  These ‘banana bags’ save people’s lives everyday.  The contents of the ‘bag’ is a recipe of essentials elements and vitamins that all life needs to properly function.  This recipe cannot be sold.  No one owns a patent on this recipe.  No one owns a patent on magnesium sulfate, folic acid, or thiamine.  This life giving ‘cocktail’ of essentials is often only administered by the Healthcare System when a person is near death.  It is used in the Emergency Room.  At other times the go to defaults for the Healthcare Industry are ineffective drugs and surgical procedures. 

Lets look at some examples.

“…Alcoholics should be administered a multivitamin preparation with sufficient quantities of thiamine and folic acid.  During alcohol withdrawal, the prophylactic administration of THIAMINE, folic acid, and pyridoxine intravenously is recommended before starting any carbohydrate-containing fluids or food.  These vitamins are often combined into a “banana bag” for intravenous administration.”

“Bariatric procedures for the treatment of morbid obesity are the most commonly performed gastrointestinal operations today, more than 34,000 procedures were done all over the world in 2011.  Sleeve gastrectomy has increased in prevalence from 0% in 2003 to 28% in 2011.”

“Weight loss surgery falls into three categories: malabsorptive, restrictive or mixed.  Procedures such as sleeve gastrectomy, Roux-en-Y gastric bypass or duodenal switch are the most frequently performed. Nevertheless, there are many procedures or modifications described like Fobi Pouch Gastric Bypass, laparoscopic gastric plication, adjustable gastric band, one anastomosis gastric bypass or ileal transposition.”

“In spite of sleeve gastrectomy being considered a restrictive procedure, …Hormonal changes have been demonstrated, and continue to be the subject of further studies, meaning that the effect of this procedure is more complex than it seems to be.

“…With the upswing of bariatric surgery, surgeons and emergency physicians should be able to diagnose and treat those complications.   Prophylactic THIAMINE should be administered to patients with predisposing factors.”

So if I have this right, there are 34,000 stomach surgeries a year for overweight people, but they aren’t checked initially for Thiamine Deficiency (TD)?  The surgeries are being performed, and then the person is given an emergency dose of Thiamin if their body starts to shut down.  Hmmm…

I wonder what one of those surgeries costs versus the price of a banana bag.

Were the patients low in Thiamine to begin with?  If not, 50% of them appear to be deficient in Thiamine after the surgery.  Thiamine is absorbed in the duodenum.  Anything interfering with the duodenum could cause TD. 


This article is called, “Fatality of Bariatric Thiamin Deficiency”

“Bariatric thiamine deficiency has been reported in as much as 49% of the patient population.  This high rate of occurrence is due to thiamine being best absorbed in the duodenum, a section that is bypassed in some bariatric surgery procedures. Thusly, absorption is decreased and thiamine levels become deficient over time.

Those with diabetes — a common comorbidity of obesity — or chronic vomiting have the greatest risk for thiamine deficiency.

Malabsorption bariatric procedures aside, the greatest cause of thiamine deficiency worldwide is poor diet. In Western countries the primary causes are alcoholism, chronic illness, and cancer. Poor diet before bariatric surgery and post-operatively increases the risk of developing bariatric thiamine deficiency.”

Sounds like they are treating symptoms of TD, or at least creating a problem that may not have existed for some people, but it does in 50% of the cases after the HC system cuts the person open.

I am taking a deep breath right now.  You might want to do the same.  Go for a walk.  Get some oxygen pumping.  Then comeback and continue.  This is a lot for me to take in and it may be for you too.


Here is a list of predisposing factors of and conditions associated with thiamine deficiency.  I have edited the source from an article to include some additional factors.  I reference the article below.

Diet of polished rice/malnutrition
Diet of carbohydrates without supplemental Thiamin
Diet without carbohydrates
Drink coffee or tea
Drink alcohol
Binge on sugar or carbohydrates
Exercise excessively

Gastrointestinal surgical procedures: gastrostomy, gastrojejunostomy, partial or subtotal colectomy, gastric bypass surgery, vertical banded gastroplasty, therapy with an intragastric balloon

Chronic alcohol abuse
Anorexia nervosa

Anorexia bulimia
Binge-eating disorder

I am also including under this category addictive behaviors, impulse behaviors, behaviors that would throw the microbiome out of balance.

Peptic ulcer, gastric cancer, colon cancer, ulcerative colitis with megacolon

Severe obesity
Recurrent vomiting or chronic diarrhea
Pyloric stenosis, peptic ulcer, drug-induced gastritis, biliary colics, Crohn’s disease
Intestinal obstruction or perforation, lithium-induced diarrhea
Pancreatitis, hyperemesis gravidarum

Cancer and related conditions: gastric carcinoma, non-Hodgkin’s lymphoma, myelomonocyitic leukemia, large B-cell lymphoma, myeloid leukemia, allogenic bone marrow transplantation/chemotherapeutics (e.g., erbulozole, ifosfamide)”

I am adding to the list constipation.  If the body is not flowing, the body will not get the nutrients it needs.  Thiamine is destroyed by bile, the Thiamine compound is torn apart by it.  If there is a back up, then the bowels are not properly functioning, and there will be limited absorption of essential nutrients.

I am adding to this list a high body burden of mercury.
Amalgam (mercury) dental fillings. 

Thiamine has a sulfur molecule in it, and mercury having an affinity for sulfur will tear the Thiamine compound apart to bind with that sulfur molecule.

Renal diseases

Aquired immunodeficiency disease

Chronic infectious febrile diseases – (Sounds daunting, right?  It means…)
CHRONIC INFECTIONS – This could include any infection.  Lyme, morgellons, candida, systemic jaw infections, MRSA
Thyrotoxicosis – (Have you ever heard of that?  The definition of it is…)
I believe these states of being, lets say a state of Thiamine Deficiency will cause a Thiamine Deficiency.  I believe the body sets itself up, it ‘rights’ itself in the water, like a boat that has been damaged, and it will stay in this stasis, floating around in a crippled state unless we consciously alter that stasis. 

It is unclear whether a bacteria like Pylori might be making Thiamine, and that the body may keep a Pyloric infection going to keep itself alive.  For example, if the host consistently wrecks the microbiome, or causes a loss of Thiamine. 

Pylori is located in the Duodenum and Stomach, right at the Pyloric valve, thus the name Pylori.  If the host, the person, is in a habit of going on ‘Benders,’ taking an action, a high dose of anything that might alter the microbiome, or the body’s Thiamine stores, the body might use the Pylori to produce Thiamine.  The metaphor I see is of having to hire bad guys to get a job done.  We might need the Pylori, the Mob so to speak, to get the goods out of port before they spoil.

The article continues:

“Thiamine and enzymes in need of thiamine as a co-factor are present in all body cells. Deficiency of thiamine affects all organ systems, particularly the cells of the nervous system (e.g., neurons and glia cells, which are supporting cells in the nervous system).

Thiamine pyrophosphate (TPP), the active form of thiamine, is a required cofactor in two enzyme-mediated carbohydrate metabolism pathways, which are the Kreb’s cycle (also known as the citric acid cycle) and Pentose phosphate pathway.  The Kreb’s cycle is a central metabolic pathway that completes the oxidative degradation of monosaccharide (carbohydrate) and other nutrients, such as fatty acids and amino acids, and occurs in the mitochondria of every cell that utilizes oxygen.” 

Our body can not run the Citric Acid Cycle without Acetyl-CoA, and it is made with Thiamine.

Acetyl-CoA may then be used in the citric acid cycle to carry out cellular respiration, so pyruvate dehydrogenase contributes to linking the glycolysis metabolic pathway to the citric acid cycle and releasing energy via NADH.

This complex is 100% Thiamine dependent

Thiamine Pyrophosphate

Thiamine Pyrophosphate, TPP, works as a coenzyme in many enzymatic reactions, such as:

Pyruvate dehydrogenase complete
Pyruvate decarboxylase in ethanol fermentation
Alpha-ketoglutarate dehydrogenase complex
Branched-chain amino acid dehydrogenase complex
2-hydroxyphytanoyl-CoA lyase

I don’t want to delve too deep into the Citric acid Cycle in this article, but it is important that we cover two of the above enzymatic reactions:

Alpha-ketoglutarate dehydrogenase
“Activity of the 2-oxoglutarate dehydrogenase complex is decreased in many neurodegenerative diseases. Alzheimer's Disease, Parkinson's Disease, Huntington Disease, and supranuclear palsy are all associated with an increased oxidative stress level in the brain.  Specifically for Alzheimer Disease patients, the activity of Oxoglutarate dehydrogenase is significantly diminished.  This leads to a possibility that the portion of the TCA cycle responsible for causing the build-up of free radical species in the brain of patients is a malfunctioning Oxoglutarate dehydrogenase complex.”

 “Tricarboxylic acid cycle enzymes following thiamine deficiency (TD) leads to memory deficits and neurological disease in animals and humans.  The thiamine-dependent enzymes of the tricarboxylic acid (TCA) cycle are reduced following Thiamine Deficiency (TD).  Also, the brains of patients that died from multiple neurodegenerative diseases often show TD.  

Whether reductions in thiamine or thiamine-dependent enzymes leads to changes in all TCA cycle (CitriCycle) enzymes has never been tested.

In the current studies, the pyruvate dehydrogenase complex (PDHC) and all of enzymes of the TCA cycle were measured in the brains of TD mice.  

Non-thiamine-dependent enzymes such as succinate dehydrogenase (SDH), succinate thiokinase (STH) and malate dehydrogenase (MDH) were altered as much or more than thiamine-dependent enzymes such as the alpha-ketoglutarate dehydrogenase complex (KGDHC) (-21.5%) and PDHC (-10.5%).

Succinate dehydrogenase (SDH) activity decreased by 27% and succinate thiokinase (STH) decreased by 24%.

The reductions in these other enzymes may result from oxidative stress because of TD or because these other enzymes of the TCA cycle are part of a metabolome that respond as a group of enzymes. The results suggest that other TCA cycle enzymes should be measured in brains from patients that died from neurological disease in which thiamine-dependent enzymes are known to be reduced.

The diminished activities of multiple TCA cycle enzymes may be important in our understanding of how metabolic lesions alter brain function in neurodegenerative disorders.”


What happened to this great research?  Sounds like Big Pharma ran out of funding that wasn’t giving them a return on their investment.  “Thank you very much for your paper on Thiamine benefits, Mr Junior Scientist.  Since you did such a great job, why don’t you study how to make a drug to treat a symptom of Thiamine deficiency.  There will be a big fat end of the year bonus for you!  In the meantime, we’ll just hold onto this paper for safekeeping.  Thank you very much.”

“ physiology of plant hormones was one of the most dynamic fields in experimental biology in the 1930s, and an important part of T. H. Morgan's influential life science division at the California Institute of Technology. I describe one episode of plant physiology research at the institution in which faculty member James Bonner discovered that the B vitamin thiamin is a plant growth regulator, and then worked in close collaboration with the Merck pharmaceutical firm to develop it as a growth-boosting agrichemical. This episode allows one to draw continuities between certain fields of life science in the United States circa 1940 and the biotechnology industry today, and also foregrounds a number of similarities between plant physiology of the late 1930s and the molecular biology of the period.”


This is a paper written in 1940 about Krebs and his study of the Citric Acid Cycle.  This link opens an excerpt on the relation of that cycle to Thiamine.

The following excerpt tells me something very specific.  It clearly states that Mice on low Thiamine diets were more likely to get Polio, however, they were dying of Thiamine Deficiency.  If a thiamine deficient mouse was not getting polio, from where was the mouse getting its energy?  I believe the mouse’s microbiome may have switched to one of fermentation, glycolysis, or like my pylori example above.  Although the mouse may have been very unhealthy, somehow it was protected from polio.  This may explain why the human has a very diverse microbiome.  We survive.  Does this mean that we should all be fermenting our guts, as many of us already do, running very inefficient citric acid cycles?  No, I don’t believe we should do this.  I don’t want to do it.  I will take my chances with Polio, if the actual research from this article is to be believed.

This is one source for the article:

“Mice given a diet deficient in thiamin showed no significant difference in susceptibility to Theiler's virus when compared with a control group receiving adequate amounts of thiamin. When the Lansing strain of poliomyelitis virus was used as the infecting agent, deficiency in thiamin intake rendered the animals less sus ceptible to infection (35 mice on a thiamin deficient diet showed no paralysis by the 14th day, while at this time 22 of 35 controls on an adequate diet were paralyzed). Many of the test animals died of thiamin deficiency, but if maintenance doses of thiamin were given, paralysis appeared in some animals after a prolonged incubation period, although a signi ficant number of animals still escaped infection. Mice fed on a diet of low calorific value but with adequate thiamin content also showed a lessened susceptibility to infection; the effect was, however, not so marked as that produced by the thiamin-deficient diet. D. J. Bauer”


Here is a great article by Tom Brimeyer about Thiamine and the Thyroid.
This is an excerpt from his article.  Please read this, and then the article in full.

Thiamine Deficiency in Disease and Testing

“Until more recently, it was commonly believed that thiamine deficiency was rare and only found prevalently among alcoholics.

More recent research, however, has helped shed some much needed light on the involvement of thiamine deficiency among other deadly diseases.

Studies have now shown that as many as 55% of cancer patients test positive for thiamine deficiency.

Other studies have shown that thiamine deficiency is found in more than 75% of diabetes (both Type 1 and Type 2).

Yet, thiamine blood tests are not necessarily accurate either.

In studies on using thiamine to treat Irritable Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS), significant benefits were seen even though the test subjects tested negative for thiamine deficiency.

So, much like thyroid hormone, it’s not necessarily how much thiamine you have in your blood that’s most important.  It’s whether or not your cells can use that thiamine.”

Tom Brimeyer briefly touches on how a Thiamine Deficiency can cause high ammonia levels in the brain.  This revelation if of great importance.

In living organisms, nitrogen arise primarily as ammonia (NH3) and ammonium (NH4+), which is a main component of the nucleic acid pool and proteins. Although nitrogen is essential for growth and maintenance in animals, but when the nitrogenous compounds exceeds the normal range which can quickly lead to toxicity and death. Urea cycle is the common pathway for the disposal of excess nitrogen through urea biosynthesis. Hyperammonemia is a consistent finding in many neurological disorders including congenital urea cycle disorders, reye’s syndrome and acute liver failure leads to deleterious effects. Hyperammonemia and liver failure results in glutamatergic neurotransmission which contributes to the alteration in the function of the glutamate-nitric oxide-cGMP pathway, modulates the important cerebral process. Even though ammonia is essential for normal functioning of the central nervous system (CNS), in particular high concentrations of ammonia exposure to the brain leads to the alterations of glutamate transport by the transporters. Several glutamate transporters have been recognized in the central nervous system and each has a unique physiological property and distribution. The loss of glutamate transporter activity in brain during acute liver failure and hyperammonemia is allied with increased extracellular brain glutamate concentrations which may be conscientious for the cerebral edema and ultimately cell death.


Ingest more Thiamine to get the ammonia levels lowered!


“…Perinatal exposure (to Mercury) led to profound deficits in juvenile hippocampal-dependent learning during training on a spatial navigation task. In aggregate, these studies indicate that exposure to one dose of MeHg during the perinatal period acutely induces apoptotic cell death, which results in later deficits in hippocampal structure and function.”

“The hippocampus belongs to the limbic system and plays important roles in the consolidation of information from short-term memory to long-term memory, and in spatial memory that enables navigation.”

“The hippocampus is anatomically connected to parts of the brain that are involved with emotional behavior…”

When we are mercury toxic, that Mercury will impinge on the sulfur in our thiamine, as the ability of a person to function is impaired.  Take a look at this article and see where the function of your body may be impaired because of a Thiamine Deficiency.


How do we get more Thiamine?  For a person with a mercury toxicity, or another habit or condition that impinges on their use of Thiamine, or our access to it, I see no other way to get enough Thiamine to correct a deficiency except by using a Thiamine Supplement.  The body supposedly has only about 20-30mcg of Thiamine in it at any one time.  However, Thiamine is also broken down to make other essential enzymes for us to function.  So for me, this in no way tells the truth as to how much Thiamine we really need.

There appears to be no toxicity level to huge intakes of Thiamine.  Supplemental Thiamine is commonly given in 100mg or even 500mg doses.  The problem will be in the absorption of said Thiamine, as our conditions/habits/symptoms will impede its absorption. 

My recommendation is to take a large dose of Thiamine, in the 100 to 500mg range.  Look for bad reactions, a redistribution of toxins, or something else that makes you feel badly.  If in 24-48 hours you are not having a bad reaction, I would do it again, and keep doing it.

Let me know how you make out with your comments and questions here.

Thank you.
Albert Wilking

Also see

Sulfur and your Skin

Autism, Ears, Smells, Sulfur, Testosterone, and Vaccines

Acute vs Chronic Mercury Poisoning

Mercury Ping Pong


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I recommend products that are natural to our well-being, and only ones that can be found in the grocery or health food store.  Everything I recommend I do myself.  Everything I do is on my website, and everyone can use my site to get back to feeling great, naturally.  However, some people can be very deep in the woods, allergic to just about everything, while suffering from chronic pain and inflammation.  Helping people naturally, takes time, patience, attention to detail, and experience.

Albert Wilking

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These links contain the basics of The Wilking Protocol.  Please read them in the order given.

The Wilking Protocol
Are You Mercury Toxic? 
Epsom Salts - Holy Grail of Healing
Salt Is Life
Potassium - Let The Truth Be Told
Vitamin C or Your Life

Magnesium, Inflammation and Nerves
The Power of Iodine

Celery, Nitrate and the Microbiome
Thiamine Saves

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